by Anne-Fleur | Mar 11, 2025 | News, Publications
Generation of chimeric antigen receptor T cells targeting p95HER2 in solid tumors PAPER Introduction The redirection of T lymphocytes against tumor-associated or tumor-specific antigens, using bispecific antibodies or chimeric antigen receptors (CAR), has shown...
by Janneke de Haan | Dec 23, 2024 | News, Publications
Imaging of tumor-associated macrophage dynamics during immunotherapy using a CD163-specific nanobody-based immunotracer JOURNAL ARTICLE ABSTRACT Immunotherapies have emerged as an effective treatment option for immune-related diseases, such as cancer and inflammatory...
by Anne-Fleur | Sep 6, 2024 | News, Publications
Specific imaging of CD8 + T-Cell dynamics with a nanobody radiotracer against human CD8β PAPER Purpose While immunotherapy has revolutionized the oncology field, variations in therapy responsiveness limit the broad applicability of these therapies. Diagnostic imaging...
by Janneke de Haan | Aug 1, 2024 | News, Publications
In-depth cross-validation of human and mouse CD4-specific minibodies for noninvasive PET imaging JOURNAL ARTICLE Abstract: In-depth cross-validation of human and mouse CD4-specific minibodies for noninvasive PET imaging of CD4+ cells and response prediction to cancer...
by Janneke de Haan | Jun 20, 2024 | News, Publications
Navigating the landscape of PD-1/PD-L1 imaging tracers: from challenges to opportunities PAPER Introduction Immunotherapy targeted to immune checkpoint inhibitors, such as the program cell death receptor (PD-1) and its ligand (PD-L1), has revolutionized cancer...
by Anne-Fleur | Jun 14, 2024 | News, Publications
Fluorescently labelled vedolizumab to visualise drug distribution and mucosal target cells in inflammatory bowel disease ABSTRACT Objective Improving patient selection and development of biological therapies such as vedolizumab in IBD requires a thorough understanding...
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