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Novel PET Imaging of Inflammatory Targets and Cells for the Diagnosis and Monitoring of Giant Cell Arteritis and Polymyalgia Rheumatica

Novel PET Imaging of Inflammatory Targets and Cells for the Diagnosis and Monitoring of Giant Cell Arteritis and Polymyalgia Rheumatica

by Janneke de Haan | Jun 6, 2022 | Publications

Novel PET Imaging of Inflammatory Targets and Cells for the Diagnosis and Monitoring of Giant Cell Arteritis and Polymyalgia Rheumatica ABSTRACT   Introduction Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two interrelated inflammatory diseases...
Phenotypic, transcriptomic and functional profiling reveal reduced activation thresholds of CD81 T cells in giant cell arteritis

Phenotypic, transcriptomic and functional profiling reveal reduced activation thresholds of CD81 T cells in giant cell arteritis

by Janneke de Haan | Apr 23, 2022 | Publications

Phenotypic, transcriptomic and functional profiling reveal reduced activation thresholds of CD81 T cells in giant cell arteritis ABSTRACT   Objectives Evidence from temporal artery tissue and blood suggests involvement of CD8þ T cells in the pathogenesis of GCA,...
Imaging and therapeutic targeting of the tumor immune microenvironment with biologics

Imaging and therapeutic targeting of the tumor immune microenvironment with biologics

by Janneke de Haan | Apr 23, 2022 | Publications

Expanding Theranostic Radiopharmaceuticals for Tumor Diagnosis and Therapy ABSTRACT   Introduction Radioligand theranostics (RT) in oncology use cancer-type specific biomarkers and molecular imaging (MI), including positron emission tomography (PET),...
Expanding Theranostic Radiopharmaceuticals for Tumor Diagnosis and Therapy

Expanding Theranostic Radiopharmaceuticals for Tumor Diagnosis and Therapy

by Janneke de Haan | Dec 22, 2021 | Publications

Expanding Theranostic Radiopharmaceuticals for Tumor Diagnosis and Therapy ABSTRACT Introduction Radioligand theranostics (RT) in oncology use cancer-type specific biomarkers and molecular imaging (MI), including positron emission tomography (PET), single-photon...
The Colony Stimulating Factor-1 Receptor (CSF-1R)-Mediated Regulation of Microglia/Macrophages as a Target for Neurological Disorders (Glioma, Stroke)

The Colony Stimulating Factor-1 Receptor (CSF-1R)-Mediated Regulation of Microglia/Macrophages as a Target for Neurological Disorders (Glioma, Stroke)

by Janneke de Haan | Dec 7, 2021 | Publications

The Colony Stimulating Factor-1 Receptor (CSF-1R)-Mediated Regulation of Microglia/Macrophages as a Target for Neurological Disorders (Glioma, Stroke) ABSTRACT Introduction Immunomodulatory therapies have fueled interest in targeting microglial cells as part of the...
A novel 18F-labeled clickable substrate for targeted imaging of SNAP-tag expressing cells by PET in vivo

A novel 18F-labeled clickable substrate for targeted imaging of SNAP-tag expressing cells by PET in vivo

by Janneke de Haan | Aug 31, 2021 | Publications

A novel 18F-labeled clickable substrate for targeted imaging of SNAP-tag expressing cells by PET in vivo ABSTRACT Introduction Bioorthogonal covalent labeling with self-labeling enzymes like SNAP-tag bears a high potential for specific targeting of cells for imaging...
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  • Interview Manfred Kneilling
  • Meet the patient: Tom van der Wal
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  • Novel PET Imaging of Inflammatory Targets and Cells for the Diagnosis and Monitoring of Giant Cell Arteritis and Polymyalgia Rheumatica
  • Phenotypic, transcriptomic and functional profiling reveal reduced activation thresholds of CD81 T cells in giant cell arteritis

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