by MarketingPNO | May 8, 2024 | News, Publications
Non-specific irreversible 89Zr-mAb uptake in tumours: evidence from biopsy-proven target-negative tumours using 89Zr-immuno-PET Abstract Background Distribution of mAbs into tumour tissue may occur via different processes contributing differently to the 89Zr-mAb...
by MarketingPNO | May 8, 2024 | News, Publications
89Zr-Immuno-PET with Immune Checkpoint Inhibitors: Measuring Target Engagement in Healthy Organs Introduction 89Zr-immuno-PET (positron emission tomography with zirconium-89-labeled monoclonal antibodies ([89Zr]Zr-mAbs)) can be used to study the biodistribution of...
by MarketingPNO | Mar 26, 2024 | News, Publications
How to obtain the image‑derived blood concentration from 89Zr‑immuno‑PET scans ABSTRACT Background PET scans using zirconium-89 labelled monoclonal antibodies (89Zr-mAbs), known as 89Zr-immuno-PET, are made to measure uptake in tumour and organ tissue. Uptake is...
by MarketingPNO | Nov 21, 2023 | News, Publications
Unveiling the potential of a macrophage-targeted PET tracer: A first-in-human study Introduction The human immune system contains a complex network of cells and organs, each with their own unique functions. Within this intricate tapestry, macrophages play an...
by MarketingPNO | Aug 15, 2023 | Publications
Phase I Study of [68Ga]Ga-Anti-CD206-sdAb for PET/CT Assessment of Protumorigenic Macrophage Presence in Solid Tumors (MMR Phase I) ABSTRACT Purpose Macrophages play an important role throughout the body. Antiinflammatory macrophages expressing the macrophage mannose...
by MarketingPNO | Mar 20, 2023 | Publications
Validation of simplified uptake measures against dynamic Patlak Ki for quantification of lesional 89Zr-Immuno-PET antibody uptake ABSTRACT Purpose Positron emission tomography imaging of zirconium-89-labelled monoclonal antibodies (89Zr-Immuno-PET) allows for...
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